New Catalytic Chemistry for Heterocycle Synthesis
Séminaire du Pr Michael F. Greaney (University of Manchester, UK)
Transition metal (TM) catalysts can control a vast range of chemical reactivity. At one extreme, they can hatness and modulate the most energetic reactive intermediates, such as arynes and carbenes. Contrastingly, they can be used to activate inert, unreactive functional groups such as C-H bonds. Both of these areas offer tremendous potential for the discovery of new, catalytic reaction pathways for C-C and C-X bond construction. Focusing on the heterocyclic field, the talk will describe our progress in designing new TM-catalysed reaction systems and their application to modular heterocycle synthesis.