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Chimie moléculaire Paris Centre
ÉCOLE DOCTORALE 406

Development of radical based synthetic strategies for the total synthesis of natural products and Posttranslational modification of proteins

Séminaire du Prof Heeyon Lee (Korean Advanced Institute of Science & Technology)

Abstract :

Tandem cycloaddition reaction of allenyldiazao precursor vis via trimethylenemethane(TMM)-diyl was developed to contruct complex polycyclic structures in a single operation. This TMM-diyl cycloaddition reaction was successfully applied to the total synthesis of natural products with very challenging structural features. Radical based C-C bond forming reaction was developed for the study of posttranslational modification (PTM) and demonstrated to mimic Lys modification in PTM.

25/09/18

Traductions :

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    cyril.ollivier@sorbonne-universite.fr (cyril.ollivier @ upmc.fr)

     

    Directeur adjoint

     

     

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    Irène Rasoarinoro (irene.rasoarinoro @ upmc.fr)

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